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Updated: Oct 6, 2026

High-throughput Purification of Affinity-tagged Recombinant Proteins
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大虫转录因子IID最大的子单元指导组装含有TBP的复合物和一个协作激活剂

R O Weinzierl1, B D Dynlacht, R Tjian

  • 1Howard Hughes Medical Institute, Department of Molecular and Cell Biology, University of California, Berkeley 94720.

Nature
|April 8, 1993
PubMed
概括

研究人员克隆了Drosophila TAFII250并组装了一个部分的TFIID复合体. 这种复合体含有TBP,TAFII110和TAFII250,支持Sp1激活,并揭示了关键的分子相互作用.

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