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Updated: Aug 18, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
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Published on: February 3, 2013

亲和成熟导致卡帕轻链转基因多个副本的差异表达

F Lozano1, C Rada, J M Jarvis

  • 1Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

Nature
|May 20, 1993
PubMed
概括

身体突变影响抗体轻链转基因表达. 在LK6小鼠中,一个转基因拷贝中的有益突变导致其他转基因拷贝的下调,影响抗体的产生.

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