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Updated: Aug 9, 2026

Generation of Human CD40-activated B cells
13:27

Generation of Human CD40-activated B cells

Published on: October 17, 2009

在辅助功能发展过程中,CD40对T细胞的联体转化共刺激

D van Essen1, H Kikutani, D Gray

  • 1Department of Immunology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

Nature
|December 7, 1995
PubMed
概括

缺乏CD40或CD40连接体的小鼠不能产生关键抗体或形成生殖中心. 在 CD40 淘汰赛小鼠中恢复 CD40 连接体信号发送启动了生殖中心的形成,突出了 T 细胞协同刺激.

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