人类白血病多重染色体转位的目标AML1,对于正常的胎儿肝脏造血是必不可少的

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Updated: May 7, 2026

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
09:01

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

T Okuda1, J van Deursen, S W Hiebert

  • 1Department of Pathology and Laboratory Medicine, St. Jude Children's Research Hospital Memphis, Tennessee 38105, USA.

Cell
|January 26, 1996
PubMed
概括

AML1转录因子对于最终的血液形成至关重要. 缺少AML1的小鼠表现出严重的造血缺陷,影响所有血细胞系,导致胚胎死亡,突出其重要作用.

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