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Cell Type-specific Gene Expression Profiling in the Mouse Liver
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肝细胞核因子1的无活化导致肝功能障碍,尿,以及脏Fanconi综合征

M Pontoglio1, J Barra, M Hadchouel

  • 1Unité des Virus Oncogènes, Département des Biotechnologies, InstitutPasteur, Paris, France.

Cell
|February 23, 1996
PubMed
概括

缺乏肝细胞核因子1 (HNF1) 的小鼠表现出肝脏扩大和衰竭,导致基尿和Fanconi综合征. 这些HNF1缺乏的小鼠可以作为研究人类脏Fanconi综合征的有价值模型.

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