跨膜氨酸酸酶DLAR控制了Drosophila中运动轴突的指导
N X Krueger1, D Van Vactor, H I Wan
1Division of Tumor Immunology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Cell
|February 23, 1996
概括
这种植物是Drosophila.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 分子生物学分子生物学
背景情况:
- DLAR是一种Drosophila中的跨膜蛋白-铁酸酶.
- 它主要表达在发育中的神经元中.
研究的目的:
- 调查DLAR在Drosophila发育过程中指导运动神经元生长的作用.
主要方法:
- 在Drosophila胚胎中对Dlar功能丧失突变的分析.
- 运动轴突路径的观察,包括分段神经b (SNb).
主要成果:
- Dlar突变导致SNb和SNd运动轴突中的路径发现错误.
- 突变者中的SNb轴突绕过它们的正常腹部点.
- 显然,SNa和SNc轴突不受Dlar突变的影响.
结论:
- DLAR对于Drosophila神经系统发育中的特定运动轴突导航选择至关重要.
- DLAR调节了某些运动神经元达到预期目标的能力.
相关概念视频
Confocal Fluorescence Microscopy
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Supercritical Fluid Chromatography
Supercritical fluid chromatography (SFC) provides a beneficial substitute for gas chromatography (GC) and liquid chromatography (LC) for certain samples because it merges the top attributes of both techniques. SFC allows the separation and analysis of compounds that GC or LC does not easily manage. These compounds are traditionally nonvolatile or thermally unstable, making GC unsuitable and lacking functional groups required for HPLC analysis.
SFC utilizes a supercritical fluid mobile phase,...
SFC utilizes a supercritical fluid mobile phase,...
PD Controller: Design
In automotive engineering, car suspension systems often employ Proportional Derivative (PD) controllers to enhance performance. PD controllers are utilized to adjust the damping force in response to road conditions. A controller, acting as an amplifier with a constant gain, demonstrates proportional control, with output directly mirroring input.
Designing a continuous-data controller requires selecting and linking components like adders and integrators, which are fundamental in Proportional,...
Designing a continuous-data controller requires selecting and linking components like adders and integrators, which are fundamental in Proportional,...
Load-frequency control
Load-frequency control (LFC) is vital for maintaining power system stability, ensuring that frequency and power flows remain within acceptable limits during load changes. Turbine-governor control eliminates rotor accelerations and decelerations following load changes. However, a steady-state frequency error persists when the change in the turbine-governor reference setting is zero. In an interconnected power system, each area agrees to export or import a scheduled amount of power through...


