运动电磁扫描预测未来的临床表现冠状动脉心脏病在高风险无症状人群
R S Blumenthal1, D M Becker, T F Moy
1Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Circulation
|March 1, 1996
概括
练习太光学扫描有效地识别了早发性冠心病患者无症状兄弟姐妹的冠心病 (CHD) 风险. 该测试对于45岁及以上的男性兄弟姐妹特别有用.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 标准运动测试在预测低风险无症状个体的冠心病 (CHD) 中存在局限性.
- 患有早发性心血管疾病的患者的兄弟姐妹代表了一个高风险群体,患有隐性心血管疾病的流行率.
- 在这个人群中早期发现隐性CHD是临床上有利的.
研究的目的:
- 评估运动光扫描在预测未来临床心脏病的有效性.
- 评估这种诊断工具在早发性心脏病患者的无症状兄弟姐妹中的有用性.
- 为了确定测试是否在高风险人群中表现更好.
主要方法:
- 在264名60岁以下无症状的个体上进行了运动光学扫描,这些人有兄弟姐妹有过早性心血管疾病的病史.
- 随访时间平均为6.2年,以记录临床心血管疾病事件的发生率.
- 异常测试结果 (运动心电图和扫描) 与未来心血管疾病的发展相关.
主要成果:
- 在264名兄弟姐妹中,有19名在平均6.2年的随访期间发展出临床心脏病.
- 异常的素扫描在男性 (29%) 比女性 (9%) 更频繁.
- 异常的质扫描显著预测了未来的心脏病 (相对风险4.7),一致的异常测试产生了14.5的相对风险,特别是在45岁以上的男性中.
结论:
- 练习太光学是早期心脏病患者无症状兄弟姐妹的风险评估的一个有用工具.
- 这种测试对45岁及以上的男性兄弟姐妹尤为有价值.
- 这种方法有助于在临床表现之前识别隐性心血管疾病的个体.
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