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在被破坏Stat6基因的小鼠中缺乏IL-4诱导的Th2反应和IgE类切换

K Shimoda1, J van Deursen, M Y Sangster

  • 1Department of Biochemistry, St Jude Children's Research Hospital, Memphis, Tennessee 38105 USA.

Nature
|April 18, 1996
PubMed
概括

信号传感器和转录6 (Stat6) 的激活器调解介素-4 (IL-4) 功能. 没有Stat6的小鼠显示Th2分化和IgE切换的缺陷,证实了Stat6的存在.

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