带有肺炎链球菌的细菌病. 对治疗和预防的影响. 弗兰克林县肺炎研究小组
J F Plouffe1, R F Breiman, R R Facklam
1Department of Internal Medicine, Ohio State University Medical Center, Columbus 43210, USA.
JAMA
|January 17, 1996
概括
肺炎 estreptococcus bacteremia 在老年人和非洲裔美国人中更常见,抗菌素耐药性增加. 肺炎球菌疫苗接种和对耐药性模式的认识对于有效治疗至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 微生物学 微生物学
背景情况:
- 肺炎 estreptococcus 是导致细菌性感染的主要原因.
- 了解S. pneumoniae的流行病学和抗菌素耐药性对于公共卫生至关重要.
研究的目的:
- 为了确定Streptococcus pneumoniae bacteremia的发病率和死亡率.
- 识别流行血清型及其抗微生物敏感性模式.
主要方法:
- 从1991年至1994年的S. pneumoniae血液分离物的未来病例确定.
- 对人口统计数据和499个分离物体的抗菌素敏感性测试进行图表审查.
主要成果:
- 在65岁以上的成年人 (83.0/100,000) 和非洲裔美国人中发生率更高.
- 感染艾滋病毒的人患艾滋病毒的风险增加了41.8倍.
- 总体死亡率为19%,随着年龄的增长而增加;到1994年,耐药菌株增加到24%.
结论:
- 增加肺炎球菌疫苗的使用和对耐药性的认识至关重要.
- 建议医生和患者对明智使用抗微生物药物的教育计划.
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Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
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