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Updated: Jul 15, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

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Published on: February 3, 2013

RAG1和RAG2蛋白质在V(D) J重组中建立了12/23规则

D C van Gent1, D A Ramsden, M Gellert

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Cell
|April 5, 1996
PubMed
概括

在RAG蛋白控制V(D) J重组特异性. 像Mg2+这样的金属离子需要12/23信号序列进行裂变,而Mn2+只需要一个信号序列进行裂变.

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