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通过视网膜母细胞瘤蛋白抑制RNA聚合酶III转录

R J White1, D Trouche, K Martin

  • 1Department of Zoology, University of Cambridge, UK. rwhite@udcf.gla.ac.uks

Nature
|July 4, 1996
PubMed
概括

视网膜母细胞瘤蛋白 (Rb) 抑制RNA聚合酶III (pol III) 转录,这是细胞生长的关键过程. 失去Rb功能会增加pol III活性,从而导致癌症细胞的不受控制的增殖.

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