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Updated: Jun 23, 2026

A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases
06:10

A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases

Published on: December 23, 2013

p53 蛋白质表现出3'-至-5'-外核酶活性

T Mummenbrauer1, F Janus, B Müller

  • 1Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Hamburg, Germany.

Cell
|June 28, 1996
PubMed
概括

瘤抑制蛋白p53表现出内在的外核酶活性,将DNA降解为脱氧核酸单酸盐. 这种新发现的野生型p53的功能扩大了其作为"基因组的守护者"的作用.

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