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Updated: Aug 8, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

Published on: January 24, 2016

Stat2和p300/CBP在干扰素α诱导的信号中进行合作

S Bhattacharya1, R Eckner, S Grossman

  • 1Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 26, 1996
PubMed
概括

腺病毒E1A蛋白通过阻断Stat2和p300/CBP之间的相互作用来抑制干扰素-α (IFN-α) 抗病毒反应. 这种干扰阻止了细胞防御基因的激活,有助于病毒复制.

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