在Xenopus中,原产地识别复合体和复制许可系统之间的相互作用

A Rowles1, J P Chong, L Brown

  • 1Imperial Cancer Research Fund, Clare Hall Laboratories, Herts, United Kingdom.

Cell
|October 18, 1996
PubMed
概括

原始识别复合体 (ORC) 对于DNA复制的启动至关重要. 在Xenopus中,XORC1的枯竭阻止了复制,ORC与染色质的结合对于许可复制起源至关重要.

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