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在防止TNF-α诱导的细胞死亡方面,NF-kappaB的重要作用

A A Beg1, D Baltimore

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|November 1, 1996
PubMed
概括

核因子卡帕B (NF-kappaB) 亚单元RelA保护细胞免受瘤坏死因子α (TNF-α) 诱导的死亡. 缺少RelA会使细胞对TNF-alpha敏感,突出显示了它在炎症疾病治疗中的作用.

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