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Updated: Aug 10, 2026

Establishing Cell Lines Overexpressing DR3 to Assess the Apoptotic Response to Anti-mitotic Therapeutics
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Published on: January 11, 2019

通过DR3进行信号转导,DR3是一种与TNFR-1和CD95相关的死亡域含受体

A M Chinnaiyan1, K O'Rourke, G L Yu

  • 1Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Sciences Inc., 9620 Medical Center Driv.

Science (New York, N.Y.)
|November 8, 1996
PubMed
概括

瘤坏死因子受体超级家族12 (TNFRSF12),也称为死亡受体3 (DR3),是一种新型的细胞因子受体. DR3信号传递涉及TRADD,TRAF2,FADD和FLICE,这表明它们在淋巴细胞平衡中起作用.

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