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Updated: Jun 22, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

剖析TNF受体1效应器功能:JNK激活与细胞亡无关,而NF-kappaB激活可以防止细胞死亡

Z G Liu1, H Hsu, D V Goeddel

  • 1Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093-0636, USA.

Cell
|November 1, 1996
PubMed
概括

瘤坏死因子受体1 (TNFR1) 触发了不同的细胞通路. 瘤坏死因子 (TNF) 信号通过RIP/TRAF2激活JNK和NF-kappaB,而FADD则调解亡,NF-kappaB保护细胞免受TNF诱导的死亡.

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