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mitra 门功能障碍是由于人造 mitra 门 chordae 的加厚和硬化造成的
Y Kobayashi1, S Nagata, F Ohmori
1Department of Internal Medicine, National Cardiovascular Center, Osaka, Japan.
Circulation
|November 1, 1996
概括
在中枢修复后人造心膜的加厚可能会损害功能,特别是与聚四乙烯 (PTFE) sutures 相比,用化染的异种心脏移植 (GTXP) 损害了心脏功能. 监测这些变化对于长期结果至关重要.
科学领域:
- 心血管外科心血管外科
- 生物材料科学 生物材料科学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 有限的数据存在于用于米特拉修复的人工的长期功能变化.
- 人工的加厚和硬化可能会随着时间的推移影响 mitra 门的功能.
- 序列回声心脏图是评估这些结构和功能变化的关键工具.
研究的目的:
- 为了评估中枢门修复后人造的加厚和硬化.
- 为了评估这些变化对中心功能的影响,使用串行心声谱.
- 为了比较甲皮的异种心脏移植 (GTXP) 与聚四乙烯 (PTFE) 的耐用性和功能效果.
主要方法:
- 对40名接受GTXP或PTFE人造膜修复的患者的回顾性分析.
- 连续的心声回声检查,以评估人造心脏的加厚和硬化 (分类等级1-3).
- 在平均6.0年 (GTXP) 和3.6年 (PTFE) 的随访期内,评估中膜区域和叶片运动的变化.
主要成果:
- 在4/7的GTXP患者和2/20的PTFE患者中发生了3级加厚和硬化 (叶片运动受损).
- 在GTXP患者 (2.5至2.1厘米) 观察到显著的关面积减少,但在PTFE患者 (2.1至2.0厘米) 没有.
- 3级变化在GTXP中比在PTFE chordae中发展得更早 (P < .05).
结论:
- 使用人造膜修复是可行的选择.
- 人工的加厚和硬化,特别是GTXP,可能导致关节功能受损.
- 修复后必须密切监测关的功能,以检测有不良变化.
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