在人类中,单击估计了末缩压力-体积关系. 一种具有非侵入性应用潜力的新方法
H Senzaki1, C H Chen, D A Kass
1Department of Internal Medicine, Johns Hopkins University Medical Institutions, Baltimore, Md, USA.
Circulation
|November 15, 1996
概括
一种新的单击方法可靠地估计人类的末压力-体积关系 (ESPVR). 这种基于正常化的时间变化的弹性曲线的方法,为非侵入性心脏功能评估提供了潜力.
科学领域:
- 心脏病学 心脏病学
- 生理学 生理学 生理学
- 生物医学工程 生物医学工程
背景情况:
- 末压力-体积关系 (ESPVR) 是心脏收缩功能的一个关键指标.
- 传统的ESPVR评估需要在不同负载下进行多次心脏循环,这限制了临床适用性.
- 开发了一种新的单击估计方法,使用正常化的人类变时弹性曲线[EN(tN]进行估计.
研究的目的:
- 开发和验证一种用于估计ESPVR的新型单击方法.
- 与传统的多节拍分析相比,评估单节拍方法的可靠性和准确性.
- 探索开发的方法的非侵入性应用的潜力.
主要方法:
- 在87名患者中使用导电导管收集了压力-体积 (PV) 数据.
- 时间变化的弹性曲线被生成,正常化,并对一致性进行分析.
- 从单个心脏周期中估计ESPVR,使用正常化的弹性曲线和特定公式.
主要成果:
- 规范化的EN(tN) 曲线在不同患者群体和疾病中表现出了显著的一致性.
- 单拍ESPVR估计显示与多拍分析结果有很高的相关性.
- 该方法准确地反映了内变化,负载的影响最小,并且优于先前的技术.
结论:
- 使用新方法,可以从人类的单个心脏周期中可靠地估计ESPVR.
- 这种单击估计技术显示出非侵入性临床应用的巨大潜力.
- 规范弹性曲线的一致性支持单拍方法的有效性.
相关概念视频
01:21Sites for measuring blood pressure
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The Brachial Artery: Primary Site for Blood Pressure Measurement
The Brachial Artery: Primary Site for Blood Pressure Measurement
01:30Equipments Used To Measure Blood Pressure
Direct Method
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This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
01:15Assessment of blood pressure in brachial artery(one-step method)
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Prepare for the Procedure:
Prepare for the Procedure:
01:23Assessment of blood pressure in brachial artery(two-step method)
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01:19Assessing Blood pressure using a doppler ultrasound
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Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
01:17Measurement of Blood Pressure
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.