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对于由于脑膜炎球菌病引起的难治性心肺呼吸衰竭的体外支持
A P Goldman1, S J Kerr, W Butt
1Great Ormond Street Hospital for Children, London, UK.
Lancet (London, England)
|February 15, 1997
概括
身体外膜氧化 (ECMO) 可以支持患有严重脑膜炎球菌疾病和心肺衰竭的儿童. 这种心肺机器疗法为那些对标准治疗无反应的重症患者提供了生存的机会.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 心肺支技术的使用.
- 传染性疾病 传染性疾病
背景情况:
- 脑膜炎球菌病导致显著的死亡率,主要是由于耐火性心肌缩,低血压和严重急性呼吸困扰综合征.
- 身体外膜氧化 (ECMO) 使用心肺机器提供临时的心脏和呼吸支持.
- 本研究回顾了英国和澳大利亚对ECMO治疗脑膜炎球菌病的经验.
研究的目的:
- 评估ECMO在患有脑膜炎球菌病和耐火性心肺衰竭的儿科患者的有效性和结果.
- 评估ECMO在严重脑膜炎球菌感染中作为救援疗法的作用.
主要方法:
- 在英国和澳大利亚,1989年至2007年期间接受ECMO治疗脑膜炎球菌病的12名儿科患者的回顾性审查.
- 分析患者人口统计,ECMO (心脏与呼吸衰竭) 的适用情况,ECMO前干预措施和结果.
主要成果:
- 12名患者 (平均年龄26个月) 接受了ECMO治疗脑膜炎球菌病.
- 七名患者因难治性休克需要早期ECMO;五名患者因呼吸衰竭需要后期ECMO.
- 在12名患者中,有8人幸存下来,在随访时有6人实现了正常生活.
结论:
- 对于患有脑膜炎球菌病的儿科患者来说,ECMO是一个可行的选择,他们经历了难以治疗的心肺呼吸衰竭.
- 考虑ECMO可能会改善严重的,治疗不耐药的脑膜炎球菌病例的生存率.
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