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Updated: Jun 18, 2026

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
18:38

Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes

Published on: September 26, 2013

冷震域蛋白LIN-28控制了C. elegans的发育时间,并由lin-4RNA调节

E G Moss1, R C Lee, V Ambros

  • 1Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA.

Cell
|March 7, 1997
PubMed
概括

在C. eleganslin-28基因的突变通过跳过幼虫阶段来加速发育. LIN-28蛋白在转录后调节中起作用,由lin-4RNA控制,以确保适当的发育时间.

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Application of RNAi and Heat-shock-induced Transcription Factor Expression to Reprogram Germ Cells to Neurons in C. elegans07:53

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