通过CD28共刺激CD4+T细胞,对HIV-1融合辅因子表达的差调节

R G Carroll1, J L Riley, B L Levine

  • 1Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville, MD 20850, USA.

Science (New York, N.Y.)
|April 11, 1997
PubMed
概括

用CD3/CD28抗体激活CD4(+) T细胞会产生对巨热性人体免疫缺陷病毒1型 (HIV-1) 的耐药性. 这通过降低关键的病毒进入因子CCR5的调节而发生,从而提供了对自然HIV-1抗性机制的见解.

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