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Updated: Mar 23, 2026

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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通过含有SMRT,mSin3A和基因素脱乙酶的复合物介导的核受体抑制

L Nagy1, H Y Kao, D Chakravarti

  • 1The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

Cell
|May 2, 1997
PubMed
概括

转录核心抑制剂SMRT和N-CoR与mSin3A和基因素脱乙酶1 (HDAC1) 相互作用,形成一个抑制剂复合体. 这种复合体对于调节激素反应基因和细胞分化至关重要.

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