预防细菌性内心炎. 美国心脏协会的建议
A S Dajani1, K A Taubert, W Wilson
1American Heart Association, Dallas, Tex 75231, USA.
JAMA
|June 11, 1997
概括
针对预防细菌性内心炎的最新指南强调风险分层和简化抗生素预防. 大多数病例与程序无关,建议明确了当抗生素预防对于有风险的患者是必要的.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 细菌内心炎预防指南上一次更新是在1990年.
- 风险人群需要更新疾病预防建议.
研究的目的:
- 更新美国心脏协会关于预防细菌内心炎的建议.
- 为有风险的个人和医疗保健从业人员提供明确的指导.
主要方法:
- 召集了一个具有内心炎专业知识的撰写小组,以及来自相关专业组织的联络成员.
- 建议是基于文献审查,体外数据,动物研究和人类病例回顾分析.
- 在 MEDLINE 搜索 (1936-1996) 中,使用关键词进行了搜索:内心炎,细菌病和抗生素预防.
主要成果:
- 大多数内心炎病例与侵入性手术无关.
- 心脏病现在被分为高,中和微不足道的风险类别.
- 需要预防的特定程序得到了澄清,口腔,牙科,胃肠道和尿生殖系统程序的简化方案.
结论:
- 更新后的建议旨在提高对预防性指示的清晰度.
- 变化包括简化剂量,删除后续剂量,以及过敏患者的替代抗生素.
- 这些修订旨在提高从业者和患者的合规性,降低成本,并尽量减少不良影响.
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