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Updated: Aug 4, 2026

Microfabrication of Chip-sized Scaffolds for Three-dimensional Cell cultivation
09:37

Microfabrication of Chip-sized Scaffolds for Three-dimensional Cell cultivation

Published on: May 12, 2008

酵母螺旋杆体围绕一个中心的Spc42p晶体组装在一起

E Bullitt1, M P Rout, J V Kilmartin

  • 1Department of Biophysics, Boston University School of Medicine, Massachusetts 02118-2394, USA.

Cell
|June 27, 1997
PubMed
概括

螺旋杆体 (SPB) 是酵母中的一个关键的微管组织中心 (MTOC),具有分层结构. 它的构造涉及子单元的结晶学包装,由冷电子显微镜揭示.

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Spindle Assembly02:50

Spindle Assembly

Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...