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用于和人类免疫缺陷病毒使用的新受体的表达克隆

H K Deng1, D Unutmaz, V N KewalRamani

  • 1Division of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, Howard Hughes Medical Institute, New York University Medical Center, New York 10016, USA.

Nature
|July 17, 1997
PubMed
概括

研究人员确定了由猿类免疫缺陷病毒 (SIV) 和HIV-2用于细胞进入的新受体. 这些发现促进了对病毒传播和获得免疫缺陷综合征 (艾滋病) 机制的理解.

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Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.