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相关概念视频

What is Gene Expression?01:42

What is Gene Expression?

197.1K
Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
197.1K
What is Gene Expression?01:36

What is Gene Expression?

11.6K
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised  of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then...
11.6K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

3.5K
No description available
3.5K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
No description available
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相关实验视频

Updated: Feb 14, 2026

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
07:09

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq

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甲类附属物进化与霍克斯基因表达的变化有关.

M Averof1, N H Patel

  • 1Wellcome/CRC Institute, Cambridge, UK.

Nature
|August 14, 1997
PubMed
概括

在甲类动物中,同源性 (Hox) 基因表达的变化与四肢修饰有关. 这表明霍克斯基因调节的变化驱动了关节动物身体计划的重大进化变化.

科学领域:

  • 发育生物学 发展生物学
  • 进化生物学 进化生物学
  • 遗传学 是一个遗传学.

背景情况:

  • 同源性 (Hox) 基因对于昆虫的细分特征至关重要.
  • 改变霍克斯基因功能的假设是推动关节动物身体计划的变化.
  • 直接证据将霍克斯基因变化与形态进化联系起来是有限的.

研究的目的:

  • 调查霍克斯基因表达变化在甲动物肢体进化中的作用.
  • 为了将特定的Hox基因 (Ubx,Abda) 的变化与形态修饰相关联.
  • 为适应性进化变化中的霍克斯基因调节提供直接证据.

主要方法:

  • 在不同类型的甲类动物中对Hox基因表达模式的比较分析.
  • 基因表达数据与胸部四肢观察到的形态差异的相关性.
  • 专注于Ultrabithorax (Ubx) 和腹部A (AbdA) 的霍克斯基因.

主要成果:

  • 观察到Ubx和Abda基因的改变表达模式之间的显著相关性.
  • 这些表达变化与前胸前四肢转化为尾动物 (食附属物) 的修饰相对应.
  • 证明了霍克斯基因调节与关节动物的主要形态变化之间的直接联系.

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Geomagnetic Field Gmf and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression
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Geomagnetic Field Gmf and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression

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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells

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相关实验视频

Last Updated: Feb 14, 2026

A Bioinformatics Pipeline for Investigating Molecular Evolution and Gene Expression using RNA-seq
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Geomagnetic Field Gmf and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression
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Geomagnetic Field Gmf and Plant Evolution: Investigating the Effects of Gmf Reversal on Arabidopsis thaliana Development and Gene Expression

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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells

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结论:

  • 霍克斯基因调节的变化与关节动物体图的显著形态变化有关.
  • 同源性基因调节可能在节肢体细分的适应性进化中起着关键作用.
  • 这项研究提供了支持霍克斯基因在进化多样化中的作用的直接证据.