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Updated: Aug 11, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

一个小G蛋白与GTPase激活蛋白rhoGAPAP复合体中的晶体结构

K Rittinger1, P A Walker, J F Eccleston

  • 1National Institute for Medical Research, London, UK.

Nature
|August 14, 1997
PubMed
概括

像Cdc42Hs这样的小G蛋白通过作为分子开关来调节细胞功能. 这项研究揭示了Cdc42Hs与GTP类似物结合的晶体结构及其与p50rhoGAP的相互作用,阐明了GTP水解调节.

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