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Updated: May 2, 2026

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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BRCA1亚核位置和酸化状态的动态变化是由DNA损伤引起的

R Scully1, J Chen, R L Ochs

  • 1The Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|August 8, 1997
PubMed
概括

在S阶段,BRCA1核焦点对DNA损伤有动态反应. 这些BRCA1复合体与受损的DNA相互作用,这表明它们在复制检查点中的作用.

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