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Updated: Aug 9, 2026

Tandem Affinity Purification of Protein Complexes from Eukaryotic Cells
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塔帕辛在多重性MHC类I-TAP复合物的组装和功能中的关键作用

B Ortmann1, J Copeman, P J Lehner

  • 1Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06510, USA.

Science (New York, N.Y.)
|August 29, 1997
PubMed
概括

塔帕辛是一种关键蛋白质,它促进了主要基因相容性复合体 (MHC) I 类分子和与抗原处理 (TAP) 相关的载体之间的相互作用. 它的表达恢复了正常的抗原呈现和免疫细胞在缺陷细胞中的识别.

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