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Updated: Jun 24, 2026

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通过双酸化来激活MAP激酶ERK2的激活机制

B J Canagarajah1, A Khokhlatchev, M H Cobb

  • 1Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 75235-9050, USA.

Cell
|September 23, 1997
PubMed
概括

线素激活蛋白 (MAP) 激酶ERK2的活性形式揭示了酸化如何激活酶. 激活唇和特异性口袋的关键结构变化解释了ERK2的存在.

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