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左心室质量与美洲印第安人的人口和血液动力学变量之间的关系:强心研究
R B Devereux1, M J Roman, G de Simone
1Department of Medicine, The New York Hospital-Cornell Medical Center, NY 10021, USA. rbdevere@mail.med.cornell.edu
Circulation
|October 7, 1997
概括
左心室质量最好通过中风体积和收缩效率来预测,人口统计学因素也发挥着作用. 近一半的心室质量变化仍然无法由这些因素解释.
科学领域:
- 心脏病学 心脏病学
- 身体生理学 身体生理学
- 生物统计学 生物统计学
背景情况:
- 以前的研究将左心室 (LV) 质量与人口统计学和血液动力学联系起来.
- 这些因素对LV质量的独立贡献以前是未知的.
研究的目的:
- 确定LV质量的人口和血液动力学预测因素的相对强度和独立性.
- 为了确定影响左心室质量的关键因素.
主要方法:
- 1935年美国印第安人参与者使用心声扫描来评估LV质量.
- 分析了LV质量和人口统计学变量,血压,中风体积 (SV) 和收缩度指标之间的关系.
- 进行了多变量分析,以确定LV质量的独立相关值.
主要成果:
- 冲击体积 (SV) 和收缩度 (压力独立的中壁分量缩短) 的测量是LV质量的更强的预测指标,而不是缩血压.
- 人口统计学变量,包括身高,体重和体重指数,也是重要的预测因素.
- 包括血液动力学和人口学因素在内的多变量模型解释了 LV 质量变化的高达 51%.
结论:
- 血液动力学因素,特别是中风体积和收缩效率,与单独的血压相比,显著改善了LV质量的预测.
- 纳入人口统计学变量进一步增强了LV质量预测.
- 左心室质量变化的很大一部分仍然无法解释,这表明涉及其他未测量的因素.
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