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Updated: Aug 18, 2026

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
09:49

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells

Published on: August 13, 2010

在生殖中心B淋巴细胞的一个子集中的V(D) J重组酶活性

S Han1, S R Dillon, B Zheng

  • 1Department of Microbiology and Immunology and Program in Molecular and Cell Biology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA.

Science (New York, N.Y.)
|October 10, 1997
PubMed
概括

生殖中心B细胞可以重新表达RAG1和RAG2基因,通过V(D) J重组实现新的抗体特异性. 这一过程,特别是在低亲和度B细胞中,允许进化飞跃,同时保持抗原选择.

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Recombinant Retroviral Production and Infection of B Cells

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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma15:07

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

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