鉴定Smad7,一个TGFβ诱导TGFβ信号传递的TGFβ抗体

A Nakao1, M Afrakhte, A Morén

  • 1Ludwig Institute for Cancer Research, Uppsala, Sweden.

Nature
|October 23, 1997
PubMed
概括

一种新型蛋白质Smad7通过阻断关键蛋白质Smad2和Smad3.3的酸化来抑制转化生长因子-β (TGF-β) 信号传递. 这一发现表明Smad7在TGF-β途径中起到负反调节者的作用.

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