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Updated: Sep 30, 2026

RhoC GTPase Activation Assay
09:58

RhoC GTPase Activation Assay

Published on: August 22, 2010

在RhoA的1.65A结构及其GTPase激活蛋白与过渡状态模拟复合体中的结构

K Rittinger1, P A Walker, J F Eccleston

  • 1National Institute for Medical Research, London, UK.

Nature
|October 24, 1997
PubMed
概括

像RhoA这样的小G蛋白通过在GTP和GDP状态之间切换来调节细胞功能. 罗GAP加速了GTP水解,其Arg85残留稳定了GTP酶活性的过渡状态.

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