内心转变的心房动:显著降低了除门与双电流通道
R A Cooper1, W M Smith, R E Ideker
1Department of Medicine, The University of Alabama at Birmingham Medical Center, 35294-0019, USA. rac@crml.uab.edu
减少自动心房除器带来的疼痛需要较低的除门. 这项研究发现,使用两个电流通路的连续冲击显著降低了心房除能量需求.
科学领域:
- 心血管研究的心血管研究.
- 医疗器械工程 医疗器械工程
- 电子生理学 电子生理学
背景情况:
- 自动心房除器需要减少疼痛才能被接受.
- 减少疼痛需要较低的除门.
- 目前的方法需要研究以提高有效性.
研究的目的:
- 为了确定连续的冲击是否会降低心房除门.
- 评估双电流通道对除的有效性.
主要方法:
- 在12只成年羊中诱导持续性心房动.
- 利用各种电极放置来进行电流输送.
- 交付的单电容双相波形 (3/1毫秒).
- 单路径和双路径连续冲击效率的比较.
主要成果:
- 双电流通道 (RAap到DCS,然后CSos到PA) 显示ED50 (0.36+/-0.13 J) 显著降低.
- 这种双通道比标准单通道 (RAap到DCS,ED50 1.31+/-0.3 J) 更有效.
- 所有其他测试的配置都比双路径方法效率低.
结论:
- 随着连续的两相冲击,心房除门显著降低.
- 与单一路径相比,使用两个当前路径显著降低了能源需求.
- 这种方法为改善心房除器性能提供了一个有希望的策略.
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