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Updated: Jul 30, 2026

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在补充C3缺乏的小鼠中,受损的巨细胞依赖的自然免疫力

A P Prodeus1, X Zhou, M Maurer

  • 1Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|November 21, 1997
PubMed
概括

补充激活对于天生的免疫力至关重要,特别是在依赖巨细胞的反应中. 在性周周周炎的模型中,补充剂缺乏显著增加了死亡率,突出了其至关重要的作用.

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Complement System01:27

Complement System

The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a membrane...