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Updated: Dec 1, 2025

Measuring Caspase Activity Using a Fluorometric Assay or Flow Cytometry
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细胞染色体c和dATP依赖的Apaf-1/caspase-9复合体的形成启动了阿波性蛋白酶级联

P Li1, D Nijhawan, I Budihardjo

  • 1Howard Hughes Medical Institute, and Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 75235, USA.

Cell
|December 9, 1997
PubMed
概括

这项研究确定了caspase-9作为亡级联中的关键蛋白质. 它激活了caspase-3,启动了由细胞染色体c和dATP触发的编程细胞死亡.

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