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Updated: Feb 7, 2026

GPI Anchoring of Proteins in the ER Membrane
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通过替代阅读框架产品p19ARFF介导的小鼠INK4a位点的瘤抑制

T Kamijo1, F Zindy, M F Roussel

  • 1Howard Hughes Medical Institute, Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Cell
|December 11, 1997
PubMed
概括

缺乏p19ARF瘤抑制剂的小鼠会发展出早期发作的瘤. 这表明p19ARF与p16INK4a一起,通过调节细胞增殖和检查点控制,对预防癌症至关重要.

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