印度已婚一夫一妻制妇女中艾滋病毒感染的传播
R R Gangakhedkar1, M E Bentley, A D Divekar
1National AIDS Research Institute, Pune, India.
JAMA
|December 24, 1997
概括
人类免疫缺陷病毒 (HIV) 在印度的非女性性工作者 (FSW) 中越来越多地被发现,配偶被确定为可能的感染源. 这凸显了改善合作伙伴通知和咨询服务的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 女性性工作者 (FSW) 和性病诊所的高艾滋病毒患病率对一般人群构成风险.
- 了解传播动态对于有针对性的干预至关重要.
研究的目的:
- 为了调查艾滋病毒和性传播疾病在低风险人群中传播.
- 为了比较印度的FSW和非FSW之间的HIV/STD流行率和风险因素.
主要方法:
- 在印度普纳市参加性病诊所的女性的前性研究 (1993-1996).
- 评估包括人口,行为,临床和实验室对性传播疾病和艾滋病毒的评估.
- 多变量分析以确定艾滋病毒感染的风险决定因素.
主要成果:
- 在FSW中,艾滋病毒的流行率明显高 (49.9%),高于非FSW (13.6%).
- 不一致的避孕套使用和生殖器病/与FSWs的HIV有关.
- 与患有性病的伴侣的性接触是非FSWs中艾滋病毒的关键风险因素.
结论:
- 在印度,非FSW人群中,艾滋病毒感染率正在上升,这挑战了以前的低风险假设.
- 配偶传播是非FSW感染HIV的可能途径.
- 加强合作伙伴通知和咨询是基本的公共卫生战略.
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