重复测量血液动力学,肌肉交感神经活动及其光谱振荡之间的关系
P van de Borne1, N Montano, B Zimmerman
1Department of Internal Medicine, and the Cardiovascular Center, University of Iowa, Iowa City 52242, USA.
Circulation
|January 7, 1998
概括
心率和肌肉交感神经活动 (MSNA) 显示短期稳定性,但长期可靠性较低. 随着时间的推移,这些尺度的自发变化与它们的光谱组成部分的平行转移相关,表明了同步.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统研究 自主神经系统研究
- 生物医学信号分析
背景情况:
- 评估心血管和神经测量的可靠性对于理解自主功能至关重要.
- 以前的研究还没有完全阐明RR间隔和肌肉交感神经活动 (MSNA) 变化的长期稳定性和相互关系.
研究的目的:
- 确定RR间隔和MSNA重复测量的短期和长期可靠性.
- 调查RR间隔和MSNA的自发波动是否反映在它们的光谱成分的变化中.
主要方法:
- 在7名健康人群中,对RR间隔和MSNA的重复测量计算了类内相关系数 (ICC).
- 呼吸,RR间隔,血压和MSNA的记录是在多个时间点 (1天,1周,1个月,3个月) 进行的.
- 线性回归分析了心血管指标变化及其光谱成分之间的关系.
主要成果:
- 对于RR间隔,血压和MSNA的短期可靠性 (ICC) 很好 (范围从0.70到0.98).
- 对于RR间变化和MSNA变化的长期可靠性是中等的 (ICC范围:0.34到0.52).
- 随机降低的RR间隔和血压与增加的同情驱动和低频与高频 (LF/HF) 的比率的平行变化有关,无论是RR间隔还是MSNA.
结论:
- 心率,MSNA及其变化在短期内是稳定的,但在长期内不那么可靠.
- 心血管测量和MSNA自发的长期变化与它们的光谱成分的变化同步.
- 这种同步表明绝对心血管参数及其随时间推移的动态光谱特征之间存在一致的关系.
相关概念视频
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