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Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

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Published on: October 22, 2012

在T细胞受体中可塑性的结构基础是识别自我-MHC抗原的受体

K C Garcia1, M Degano, L R Pease

  • 1Department of Molecular Biology and the Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 21, 1998
PubMed
概括

T细胞受体 (TCRs) 通过经历形状变化来识别多种自我和外来抗原来表现出双重特异性. 这种结构可塑性允许TCR扫描-MHC复合体以检测病原体.

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