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Updated: Sep 10, 2026

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
06:25

Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining

Published on: December 23, 2016

在感染SIV的 rhesus macaques 中,T淋巴细胞的快速循环

H Mohri1, S Bonhoeffer, S Monard

  • 1Aaron Diamond AIDS Research Center, The Rockefeller University, 455 First Avenue, New York, NY 10016, USA.

Science (New York, N.Y.)
|March 21, 1998
PubMed
概括

猿类免疫缺陷病毒 (SIV) 感染的淋巴细胞周转率显著增加,影响CD4和CD8T细胞,NK细胞和B细胞,表明普遍的免疫激活.

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Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...