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可行的心肌:流行病学,检测和临床影响
1Department of Cardiology, Cleveland Clinic Foundation, OH 44195, USA.
Lancet (London, England)
|March 31, 1998
概括
心肌梗塞 (MI) 的幸存者可能患上心力衰竭,但可行的心肌可以恢复. 重新评估MI治疗以识别和挽救这种组织可以改善患者的治疗结果和预后.
科学领域:
- 心脏病学 心脏病学
- 再生医学是一种再生医学.
背景情况:
- 心肌梗塞 (MI) 疗法降低了死亡率,但幸存者往往患有心力衰竭.
- 目前治疗心力衰竭后心脏病发作的医疗方法的疗效有限.
- 心脏移植是对末期心力衰竭的有限选择.
研究的目的:
- 重新评估心肌梗塞目前的治疗方法.
- 为了检查可行的心肌复苏后心肌病的发病因子.
- 审查识别可挽救心脏组织的技术,并讨论临床影响.
主要方法:
- 关于心肌梗塞病原和恢复的文献综述.
- 分析识别可行的心肌细胞的技术.
- 对可挽救组织的临床影响的评估.
主要成果:
- 大约40%的心肌梗塞受影响的部分可能会自发恢复或经过再血管化.
- 可行的心肌固性挑战了以前对缺血性损伤的理解.
- 心肌再血管化可以改善某些患者的症状,运动能力和预后.
结论:
- 识别和挽救可行的心肌梗塞后心肌梗塞至关重要.
- 对于具有可活组织的患者,应考虑再血管化策略.
- 对可挽救的心肌的进一步研究可以优化心力衰竭管理.
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