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Updated: Aug 17, 2026

Induction and Testing of Hypoxia in Cell Culture
07:01

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Published on: August 12, 2011

通过低氧诱导因子1alpha稳定野生类型的p53

W G An1, M Kanekal, M C Simon

  • 1Department of Cell and Cancer Biology, Medicine Branch, NCI, NIH, Bethesda, Maryland 20892, USA.

Nature
|April 16, 1998
PubMed
概括

缺氧,或低氧,通过一种涉及缺氧诱导因子1-alpha (HIF-1alpha) 的机制诱导野生型p53基因表达. 这项研究表明,HIF-1alpha稳定了p53蛋白,导致其积累和激活.

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