Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.4K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.4K
Tumor Immunotherapy01:27

Tumor Immunotherapy

842
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
842
Gene Therapy00:59

Gene Therapy

26.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
26.6K
Stem Cell Culture01:17

Stem Cell Culture

5.8K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.8K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.1K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.1K
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

5.2K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
5.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Low-frequency genetic variants in GAK enhance Golgi function and protect against Parkinson's disease.

medRxiv : the preprint server for health sciences·2025
Same author

An in vitro model of lissencephaly: expanding the role of DCX during neurogenesis.

Molecular psychiatry·2017
Same author

Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium.

Molecular psychiatry·2017
Same author

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology.

Molecular psychiatry·2016
Same author

The different moods of human serotonergic neurons.

Molecular psychiatry·2015
Same author

Generation of functional human serotonergic neurons from fibroblasts.

Molecular psychiatry·2015
Same journal

Six ways to put the public at the heart of science and policy.

Nature·2026
Same journal

The complex truth about trust in science.

Nature·2026
Same journal

Have people stopped trusting science? The data tell a surprising story.

Nature·2026
Same journal

How FAIR data are helping to build trust in science.

Nature·2026
Same journal

Scientists should recognize their own political biases to build public trust.

Nature·2026
Same journal

Harmonizing standards and resources for the medical genome.

Nature·2026
查看所有相关文章

相关实验视频

Updated: Nov 14, 2025

Enhancing Chimeric Antigen Receptor-Extracellular Vesicles (CAR-EV) Technology: The Future of Cancer Therapy
07:33

Enhancing Chimeric Antigen Receptor-Extracellular Vesicles (CAR-EV) Technology: The Future of Cancer Therapy

Published on: September 19, 2025

432

细胞疗法是一种细胞疗法.

F H Gage1

  • 1Laboratory of Genetics, The Salk Institute, La Jolla, California 92037, USA.

Nature
|May 14, 1998
PubMed
概括
此摘要是机器生成的。

细胞疗法为各种疾病提供了有前途的治疗方法. 最佳的细胞类型取决于具体的疾病及其所需的功能,解决兼容性和安全性的关键挑战.

更多相关视频

Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells
10:04

Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells

Published on: August 1, 2025

1.1K
Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

670

相关实验视频

Last Updated: Nov 14, 2025

Enhancing Chimeric Antigen Receptor-Extracellular Vesicles (CAR-EV) Technology: The Future of Cancer Therapy
07:33

Enhancing Chimeric Antigen Receptor-Extracellular Vesicles (CAR-EV) Technology: The Future of Cancer Therapy

Published on: September 19, 2025

432
Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells
10:04

Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells

Published on: August 1, 2025

1.1K
Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

670

科学领域:

  • 再生医学是一种再生医学.
  • 免疫学 免疫学 免疫学
  • 生物技术是生物技术.

背景情况:

  • 细胞疗法是治疗人类疾病的快速发展领域.
  • 细胞疗法的有效性高度依赖于特定的细胞类型及其预期功能.
  • 仍然存在重大挑战,包括免疫学兼容性,体外细胞扩张和质量控制.

研究的目的:

  • 突出细胞源和功能在为特定疾病量身定制细胞疗法的重要性.
  • 解决阻碍细胞疗法的广泛应用的关键问题.
  • 强调需要克服当前局限性的跨学科方法.

主要方法:

  • 审查当前的细胞治疗策略和挑战.
  • 对影响治疗应用的细胞类型选择因素的分析.
  • 讨论解决免疫学,制造和安全问题的进展.

主要成果:

  • 没有一种通用细胞类型适合所有疾病;来源和功能是关键的决定因素.
  • 在克服免疫障碍和改善体外细胞繁殖方面取得了进展.
  • 通过跨学科合作,正在积极开发质量控制和安全措施.

结论:

  • 基于疾病要求的个性化细胞选择对于有效的细胞疗法至关重要.
  • 跨学科的努力对于通过解决安全性,疗效和可扩展性来推进细胞治疗至关重要.
  • 持续的研究和合作将为细胞治疗的更广泛的临床应用铺平道路.