心脏骤停发生的循环节变化:初始和重复的发作
M Peckova1, C E Fahrenbruch, L A Cobb
1Department of Biostatistics, University of Washington, Seattle 98105-4689, USA.
Circulation
|July 17, 1998
概括
心脏骤停表现出日常模式,在早上和晚上达到峰值,并且与日常活动有关. 经常性心脏骤停没有显示出时间关联,除了女性.
科学领域:
- 心脏病学 心脏病学
- 时间生物学 时间生物学
- 公共卫生 公共卫生
背景情况:
- 了解心脏骤停发作的时间模式对于阐明急性心血管疾病机制至关重要.
- 之前的研究表明,心脏骤停发病率的日间和季节性变化,在早上和晚上达到峰值.
- 白天时间和复发性心脏骤停之间的关系仍然没有被检查.
研究的目的:
- 为了研究医院外心脏骤停的时间变化.
- 为了检查一天中的时间和经常性心脏骤停之间的关联.
主要方法:
- 分析了西雅图消防部门参与的6603例医院外心脏骤停病例.
- 时间模式的检查,包括日间变化和反复停止时间.
- 统计分析以心律和存活率进行调整.
主要成果:
- 心脏骤停表现为白天变化,有两个峰值 (8-11 AM和4-7 PM) 和较低的夜间发病率.
- 晚上的峰值主要与心室动有关,而早上的峰值显示了其他节奏.
- 心脏骤停与存活率显示出更明显的日间变化;除了女性外,对于复发性骤停没有发现总体时间关联.
结论:
- 心脏骤停遵循可预测的日常模式,可能受到日常活动的影响.
- 这些发现支持了外在活动,而不是仅仅是疾病特征,可能引发心脏骤停的假设.
- 在反复逮捕中缺乏关联表明活动触发事件,在女性中观察到一个特定的模式.
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