在侵袭性儿科癌症中,hSNF5/INI1的切断突变

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Updated: Oct 29, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
09:37

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

Published on: August 25, 2021

I Versteege1, N Sévenet, J Lange

  • 1Laboratoire de Pathologie Moléculaire des Cancers, Section de Recherche, Institut Curie, Paris, France.

Nature
|July 22, 1998
PubMed
概括

恶性形瘤 (MRT) 是一种具有侵略性的儿童癌症. 瘤抑制剂hSNF5/INI1基因的丧失与MRT的发展有关,这表明它在瘤发生中的作用.

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