出版偏见和被动吸烟研究:已发表和未发表研究的比较
1Institute for Health Policy Studies, University of California, San Francisco, 94109, USA.
JAMA
|July 24, 1998
概括
出版偏见影响研究评论. 关于被动吸烟的研究没有显著的结果经历了比那些有重大发现的研究更长的出版延迟,影响了科学文献.
科学领域:
- 环境健康 环境健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 发表延迟和忽略不重要的结果可能会导致科学评论产生偏见.
- 了解出版模式对于准确的科学解释至关重要.
研究的目的:
- 评估关于被动吸烟对健康影响的未发表研究的程度.
- 调查是否有无意义结果的被动吸烟研究与具有统计学意义结果的研究相比,出版的时间更长.
主要方法:
- 用半结构化的电话采访方法与主要调查人员联系.
- 收集了1981年至1995年间资助的61项关于被动吸烟对健康影响的研究.
- 收集关于出版时间和统计学意义的数据进行分析.
主要成果:
- 在61项研究中,有14项仍未发表.
- 没有显著结果的研究的出版时间中位数为5年,而显著结果的出版时间为3年 (P=.004).
- 统计学意义,实验设计,较小的研究规模和动物受试者预测的出版时间.
结论:
- 对于报告无意义发现的被动吸烟研究,存在着显著的出版延迟.
- 这种延迟表明了该领域潜在的出版偏见.
- 确保及时公布所有结果对于公正的科学理解至关重要.
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