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Updated: Aug 16, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
15:07

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

在骨B淋巴细胞中,V(D) J重组酶诱导被抗原受体信号抑制

M Hertz1, V Kouskoff, T Nakamura

  • 1National Jewish Medical and Research Center, Division of Basic Sciences, Department of Pediatrics, Denver, Colorado 80206, USA.

Nature
|July 31, 1998
PubMed
概括

B细胞抗原受体 (BCR) 信号调节B淋巴细胞中的DNA重组. 这个被称为V(D) J重组的过程对于免疫耐受性和免疫反应至关重要,但其诱导在不成熟和成熟细胞之间有所不同.

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